A type IV pilin, PilA, Contributes To Adherence of Burkholderia pseudomallei and virulence in vivo.
Infect Immun
; 73(2): 1260-4, 2005 Feb.
Article
en En
| MEDLINE
| ID: mdl-15664977
ABSTRACT
The Burkholderia pseudomallei K96243 genome contains multiple type IV pilin-associated loci, including one encoding a putative pilus structural protein (pilA). A pilA deletion mutant has reduced adherence to human epithelial cells and is less virulent in the nematode model of virulence and the murine model of melioidosis, suggesting a role for type IV pili in B. pseudomallei virulence.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Adhesión Bacteriana
/
Burkholderia pseudomallei
/
Fimbrias Bacterianas
/
Proteínas Fimbrias
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Infect Immun
Año:
2005
Tipo del documento:
Article
País de afiliación:
Reino Unido