Kefir yeast technology: scale-up in SCP production using milk whey.
Biotechnol Bioeng
; 89(7): 788-96, 2005 Mar 30.
Article
en En
| MEDLINE
| ID: mdl-15688361
ABSTRACT
A three-step process to scale-up kefir biomass production at a semi-industrial scale employing whey is reported. Aerobic fermentations were initially performed at laboratory scales, in 1.5- and 4-L bioreactors, yielding 79 g/L final kefir biomass (0.89 g/g of lactose utilized), in 7 h of fermentation time. The use of whey as carbon source even in solid cultures led to the formation of a granular biomass. These results encouraged scale-up at a semi-industrial-scale pilot plant employing 100- and 3,000-L bioreactors, leading to the development of a process for granular kefir biomass production. The results validated the laboratory-scale experiments and the avoidance of centrifugal separators due to granular biomass formation. Pilot-plant operations showed kefir to be highly resistant to contamination under actual industrial conditions and no serious problems in handling of raw materials and equipment were observed. Economic analysis showed a 20% higher cost of the market price of products, with added value of up to 15.9 x 10(9) within the European Union.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saccharomyces cerevisiae
/
Biotecnología
/
Reactores Biológicos
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Productos Lácteos Cultivados
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Proteínas de la Leche
Idioma:
En
Revista:
Biotechnol Bioeng
Año:
2005
Tipo del documento:
Article