Synthesis of functionalized nitroarylmagnesium halides via an iodine-magnesium exchange.

Sapountzis, Ioannis; Dube, Henry; Lewis, Robert; Gommermann, Nina; Knochel, Paul

Sapountzis, Ioannis; Dube, Henry; Lewis, Robert; Gommermann, Nina; Knochel, Paul.

Afiliación

Sapountzis I; Department Chemie, Ludwig-Maximilians-University, Butenandtstrasse 5-13, 81377 Munich, Germany.

J Org Chem ; 70(7): 2445-54, 2005 Apr 01.

Article en En | MEDLINE | ID: mdl-15787530

ABSTRACT

ABSTRACT

[reaction see text] Various nitro-substituted aryl and heteroaryl iodides undergo an iodine-magnesium exchange reaction when treated with PhMgCl leading to nitro-containing magnesium organometallics. These Grignard reagents display an excellent stability at temperatures below -40 degrees C and do not undergo electron-transfer reactions. They react as expected with various electrophiles.

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Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Org Chem Año: 2005 Tipo del documento: Article País de afiliación: Alemania

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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Org Chem Año: 2005 Tipo del documento: Article País de afiliación: Alemania