Role of low-osmolality contrast media in thromboembolic complications: scanning electron microscopy study.
Radiology
; 183(3): 741-4, 1992 Jun.
Article
en En
| MEDLINE
| ID: mdl-1584930
ABSTRACT
Numerous in vitro studies have found that clot formation may occur when blood is mixed directly with nonionic low-osmolality contrast media during angiographic procedures because of activation of hemostasis in the catheter; ionic contrast media, on the other hand, inhibit clot formation. Thirty patients were injected with low-osmolality contrast media--15 with ioxaglate, an ionic dimer, and 15 with iopamidol, a nonionic monomer. The inner wall of the angiographic catheter was studied with electron microscopy after selective catheterization of supraaortic vessels. Clot formation of various extent was observed in nine (60%) of the patients administered iopamidol. No coagulation process was found in the catheters of the patients administered ioxaglate. Results indicate that nonionic, low-osmolality contrast media may play a role in the formation of thromboembolisms.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tromboembolia
/
Yopamidol
/
Ácido Yoxáglico
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Radiology
Año:
1992
Tipo del documento:
Article
País de afiliación:
Italia