[Quantitative analysis of serum troponin I and myoglobin in patients with acute myocardial infarction].
Di Yi Jun Yi Da Xue Xue Bao
; 25(5): 550-1, 2005 May.
Article
en Zh
| MEDLINE
| ID: mdl-15897132
ABSTRACT
OBJECTIVE:
To investigate the clinical implications of cardiac troponin I (cTnI), myoglobin (Mb), creatine kinase (CK) and creatine kinase isoenzyme (CK-MB) in patients with acute myocardial infarction (AMI).METHODS:
The serum concentrations of cTnI and Mb were determined in 50 patients with AMI 2 to 4 h after chest pain onset and compared with those measured in 50 age-matched healthy subjects.RESULTS:
The serum levels of cTnI, CK-MB and CK in patients with AMI were significantly higher than those in the control group. Mb levels in AMI group were above the normal range. Mb, CK-MB, CK and cTnI reached the peak levels at 8+/-2.2, 18.1+/-3.2, 19.4+/-4.1 and 18.6+/-2.9 h after the onset, respectively, and their levels increased with the aggravation of AMI and were reduced to the normal levels with the amelioration of the disease. All the 4 indices were normal in the control group.CONCLUSION:
cTnI and Mb are reliable biochemical markers for early diagnosis of AMI and the changes in their serum levels have clinical significance in diagnoses and prognostic judgment of AMI.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Troponina I
/
Infarto del Miocardio
/
Mioglobina
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Di Yi Jun Yi Da Xue Xue Bao
Asunto de la revista:
MEDICINA
Año:
2005
Tipo del documento:
Article
País de afiliación:
China