Normal growth rate in rats is recovered after a period of zinc deficiency by restoration of zinc supply by means of a zinc-fortified Petit Suisse cheese.
Biol Trace Elem Res
; 104(3): 269-73, 2005 Jun.
Article
en En
| MEDLINE
| ID: mdl-15930596
ABSTRACT
Fortification of a Petit Suisse cheese with zinc sulfate and zinc gluconate stabilized with glycine was used as a tool to overcome zinc-deficiency effects on total-body growth and skeletal growth. Animals were divided in 4 groups of 10 rats basal (B), control (C), depletion-repletion 1 (DR1), and depletion-repletion 2 (DR2). These four groups were fed with four diets basal (2 ppm Zn), control (30 ppm Zn), DR1, and DR2; they received a basal diet for 14 d and a control diet for the other 14 d of the experiment, using zinc sulfate for DR1 and zinc gluconate stabilized with glycine for DR2. After 28 d of the experiment, total-body weight and weight gain of the control and DR1 and DR2 animals were not statistically different (p<0.05), Femur weight and femur zinc content of DR1 and DR2 did not achieve the values of control animals (p<0.05), but they were higher than that of basal animals. Our results show that restoration of dietary zinc levels by means of food fortification normalized weight gain, as an indicator of total-body growth, and presented a trend to normalize bone weight, as a marker of skeletal growth, in young rats and independently of the zinc source used.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Zinc
/
Alimentos Fortificados
/
Queso
/
Sulfato de Zinc
/
Enfermedades Carenciales
Límite:
Animals
Idioma:
En
Revista:
Biol Trace Elem Res
Año:
2005
Tipo del documento:
Article
País de afiliación:
Argentina