Chromosomics.
Cytogenet Genome Res
; 111(2): 101-6, 2005.
Article
en En
| MEDLINE
| ID: mdl-16103649
ABSTRACT
The term "chromosomics" is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner during the cell cycle. It also deals with species-specific differences in the architecture of chromosomes, which has been overlooked in the past. Chromosomics includes research into chromatin-modification-mediated changes in the architecture of chromosomes, which may influence the functions and life-spans of cells, tissues, organs and individuals. It also addresses the occurrence and prevalence of chromosomal gaps and breaks.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cromosomas
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Cytogenet Genome Res
Asunto de la revista:
GENETICA
Año:
2005
Tipo del documento:
Article
País de afiliación:
Alemania