A phase-switch purification approach for the expedient removal of tagged reagents and scavengers following their application in organic synthesis.
Org Biomol Chem
; 3(17): 3140-60, 2005 Sep 07.
Article
en En
| MEDLINE
| ID: mdl-16106295
ABSTRACT
In this paper we wish to report on a variety of expedient chemical transformations and purifications achieved via a generic "catch and release" methodology, based on a synthetically inert bipyridyl chelating tag that can be selectively captured with a resin-bound copper(II) species. Utilising this approach we are able to derive many of the same benefits associated with both solid phase synthesis and supported reagent methods.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Organometálicos
/
2,2'-Dipiridil
/
Cobre
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2005
Tipo del documento:
Article
País de afiliación:
Reino Unido