Cognitive correlates of cerebral white matter lesions and water diffusion tensor parameters in community-dwelling older people.
Cerebrovasc Dis
; 20(5): 310-8, 2005.
Article
en En
| MEDLINE
| ID: mdl-16141715
ABSTRACT
BACKGROUND:
The biological basis of cognitive ageing is unknown. One underlying process might be disruption of white matter tracts connecting cortical regions. White matter lesions (WML) seen on structural MRI may disrupt cortical connections, but diffusion tensor MRI (DT-MRI) parameters - mean diffusivity (METHODS:
105 community-dwelling volunteers underwent MRI and neuropsychological assessment. Seventy-two (68.6%) were female, and their mean age was 78.4 (SD 1.5) years. Scans were rated for WML load.RESULTS:
CONCLUSIONS:
DT-MRI parameters, in particular
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Trastornos del Conocimiento
/
Imagen de Difusión por Resonancia Magnética
/
Fibras Nerviosas Mielínicas
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Cerebrovasc Dis
Asunto de la revista:
ANGIOLOGIA
/
CEREBRO
Año:
2005
Tipo del documento:
Article
País de afiliación:
Reino Unido