Effect of carotid artery ligation on regional cerebral blood flow in normotensive and spontaneously hypertensive rats.
Stroke
; 8(3): 374-9, 1977.
Article
en En
| MEDLINE
| ID: mdl-16364
ABSTRACT
Regional cerebral blood flow (rCBF) was measured in normotensive rate (NTR) and spontaneously hypertensive rats (SHR), in a lightly anesthetized state and with control of PaCO2 by artificial ventilation. Without carotid artery ligation, NTR and SHR showed almost identical rCBF values and distribution, despite significantly elevated levels of blood pressure in SHR. Bilateral carotid artery ligation, however, caused much more pronounced decreases of rCBF (ischemia) in SHR than NTR, in regions supplied by the carotid artery. The reduction of rCBF in SHR was rather homogenous and symmetrical. Mechanisms causing the differences between NTR and SHR are discussed.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Arterias Carótidas
/
Circulación Cerebrovascular
/
Hipertensión
Límite:
Animals
Idioma:
En
Revista:
Stroke
Año:
1977
Tipo del documento:
Article