Spontaneous remission of acute myeloid leukemia associated with GnRH agonist treatment.
Leuk Lymphoma
; 47(3): 557-60, 2006 Mar.
Article
en En
| MEDLINE
| ID: mdl-16396781
ABSTRACT
Spontaneous remission of acute myeloid leukemia (AML) in adults is a rare but well documented phenomenon. This study reports on a 64-year-old male patient with acute myelogenous leukemia (AML-M4, according to the French-American-British classification) that was developed on a background of chronic myelomonocytic leukemia (CMML) and then underwent remission after treatment with the gonadotropin-releasing hormone agonist (GnRH agonist) triptorelin for presumed prostate cancer. Remission persisted for at least 4 years before the patient was lost to follow-up. To the author' knowledge, this is the first report of remission in an AML-M4 case associated with hormone manipulation. Possible mechanisms of this phenomenon are discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Leucemia Mielomonocítica Aguda
/
Leucemia Mielomonocítica Crónica
/
Hormona Liberadora de Gonadotropina
/
Pamoato de Triptorelina
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Leuk Lymphoma
Asunto de la revista:
HEMATOLOGIA
/
NEOPLASIAS
Año:
2006
Tipo del documento:
Article
País de afiliación:
Grecia