Hippocampal atrophy in Alzheimer disease: age matters.
Neurology
; 66(2): 236-8, 2006 Jan 24.
Article
en En
| MEDLINE
| ID: mdl-16434661
ABSTRACT
Hippocampal atrophy is a marker of Alzheimer disease (AD). It remains unclear whether this holds true for younger patients as well. Hippocampal volume was measured on MRI scans of 103 clinically diagnosed AD patients and 73 controls (aged 51 to 85 years). Aging and AD were independently associated with smaller hippocampal volume. Both young and old AD patients have hippocampal atrophy abnormal for age. Age-dependent criteria for hippocampal atrophy, suggestive of AD, are needed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Imagen por Resonancia Magnética
/
Enfermedad de Alzheimer
/
Hipocampo
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neurology
Año:
2006
Tipo del documento:
Article
País de afiliación:
Países Bajos