[Transfusion-related acute lung injury (TRALI): emerging or main transfusion hazard?]. / Le syndrome respiratoire aigu post- transfusionnel (TRALI): complication émergente ou principale des transfusions?

Transfusion-Related Acute Lung Injury or TRALI is one of the most frequent severe transfusion reactions ( one third of Non Hemolytic Febrile Transfusion Reactions). It presents as a generally mild form of acute respiratory distress syndrome occurring 1 to 2 hours after transfusion of a plasma-containing blood component. This transfusion reaction appears, most of the time, in patients with focal inflammation and is of good prognosis when adequately diagnosed and treated. TRALI prevention rests on donor selection for plasma donation, hemovigilance system effectiveness and restrictive transfusion strategy.