Intravenous thrombolytic therapy in patients with phlegmasia caerulea dolens.

In a prospective study, nine patients with phlegmasia caerulea dolens (PCD) related to iliac occlusive thrombosis were treated with intravenous thrombolysis. After thrombolysis, despite no significant improvement in the Marder score value, progression to venous gangrene, major hemorrhage or death was not observed and no amputation was needed. Intravenous thrombolysis should be seriously considered in patients with PCD.