Alpha-glucosidase inhibitory anthranols, kenganthranols A-C, from the stem bark of Harungana madagascariensis.
J Nat Prod
; 69(2): 229-33, 2006 Feb.
Article
en En
| MEDLINE
| ID: mdl-16499321
ABSTRACT
One new prenylated 1,4-anthraquinone and three new prenylated anthranols, named kengaquinone (1) and kenganthranols A (2), B (3), and C (4), were isolated from a hexane extract of the stem bark of Harungana madagascariensis. Six known compounds including anthraquinones, anthrones, and xanthones were also isolated and identified. The structures of the new compounds were determined by analysis of spectroscopic data and comparison with data of previously known analogues. Some isolated compounds (3-5, 7-11) were evaluated for their alpha-glucosidase inhibition activity. Compounds 3, 4, 8, and 11 showed significant activity, whereas compounds 7, 9, and 10 were inactive in this test.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plantas Medicinales
/
Antraquinonas
/
Clusiaceae
/
Inhibidores Enzimáticos
/
Alfa-Glucosidasas
País/Región como asunto:
Africa
Idioma:
En
Revista:
J Nat Prod
Año:
2006
Tipo del documento:
Article
País de afiliación:
Camerún