Quinol fatty alcohols as promoters of axonal growth.
Bioorg Med Chem Lett
; 16(10): 2637-40, 2006 May 15.
Article
en En
| MEDLINE
| ID: mdl-16517160
ABSTRACT
The synthesis of three series of quinol fatty alcohols (QFAs) and their biological activities on the promotion of axonal growth are described. Interestingly, the 15-(2,5-dimethoxyphenyl)pentadecan-1-ol, the QFA bearing 15 carbon atoms on the side chain (n=15), shows the most potent promotion of axonal growth in the presence of both permissive and non-permissive naturally occurring substrates such as Sema3A and myelin proteins.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Axones
/
Hidroquinonas
Idioma:
En
Revista:
Bioorg Med Chem Lett
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Francia