Combined diphtheria-tetanus-pertussis vaccine for tetanus-prone wound management in adults.
Eur J Emerg Med
; 13(2): 67-71, 2006 Apr.
Article
en En
| MEDLINE
| ID: mdl-16525231
ABSTRACT
INTRODUCTION:
Booster vaccination against tetanus, diphtheria and pertussis is recommended throughout life. Adults are difficult to reach and vaccination coverage in this group is often inadequate. The use of a reduced-antigen content combined diphtheria-tetanus-acellular pertussis ('adult' dTpa) vaccine for tetanus prophylaxis in emergency room wound management provides an opportunity to boost immunity against three infections simultaneously, thereby optimizing the efficiency of medical interventions with adults assessed.METHODS:
A single-blind, randomized, controlled study of 320 healthy adults, the anti-tetanus antibody response within 10 days following vaccination with Boostrix (reduced-antigen diphtheria-tetanus-acellular pertussis).RESULTS:
The anti-tetanus antibody response to the reduced-antigen diptheria-tetanus-acellular pertussis vaccine was equivalent to Tetavax, a licensed monovalent tetanus-toxoid vaccine.CONCLUSION:
The use of diphtheria-tetanus-acellular pertussis is a safe and effective way to provide vaccination to adults against three diseases during emergency room visits for wound management.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tétanos
/
Vacuna contra Difteria, Tétanos y Tos Ferina
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur J Emerg Med
Asunto de la revista:
MEDICINA DE EMERGENCIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Noruega