Nitric oxide in serum and renal tissue during compensatory renal hypertrophy in rats.
Bosn J Basic Med Sci
; 6(1): 46-9, 2006 Feb.
Article
en En
| MEDLINE
| ID: mdl-16533179
ABSTRACT
Nitric oxide (NO) level in serum and renal tissue has been examined in 15 male Wistar rats, body weight 200-250 g, 7 days after unilateral nephrectomy. All rats were ether-anaesthetized and the kidneys were removed by dorsolateral approach. NO concentration in serum and renal tissue was determined by classic colorimetric Griess reaction. Conversion of NO(3)(2-) into NO(2)(2-) was done with elementary zinc. Results have shown that NO concentration in renal tissue is statistically higher in rats 7 days after unilateral nephrectomy then in control renal tissue before compensatory kidney growth (p<0,02). There is no difference between NO concentration in serum before unilateral nephrectomy and 7 days after nephrectomy. These findings suggest that NO may play an important role in mediating the hemodynamic changes associated with reduced renal mass.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Riñón
/
Óxido Nítrico
Límite:
Animals
Idioma:
En
Revista:
Bosn J Basic Med Sci
Asunto de la revista:
MEDICINA
Año:
2006
Tipo del documento:
Article