Corticotropin-producing pulmonary gangliocytic paraganglioma associated with Cushing's syndrome.
Hum Pathol
; 37(5): 623-6, 2006 May.
Article
en En
| MEDLINE
| ID: mdl-16647961
ABSTRACT
Gangliocytic paraganglioma (GP) is an unusual tumor in the wide spectrum of neuroendocrine neoplasms. The biologic behavior and histogenesis of this tumor is uncertain because, despite its benign histologic features, there have been reports of metastases to regional lymph nodes and distant metastases. Although most of these tumors have been reported in the duodenum, examples of GP arising in extra-ampullary sites have been well documented. Herein, we report the case of a lung GP corticotropin producing and presenting as Cushing's syndrome. After removal of the tumor, there was a significant drop in cortisol and corticotropin levels. To our knowledge, this is the first report of a GP causing Cushing's syndrome.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Paraganglioma
/
Hormona Adrenocorticotrópica
/
Síndrome de Cushing
/
Neoplasias Pulmonares
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Hum Pathol
Asunto de la revista:
PATOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos