Evaluation of acute perihematomal regional apparent diffusion coefficient abnormalities by diffusion-weighted imaging.
Acta Neurochir Suppl
; 96: 81-4, 2006.
Article
en En
| MEDLINE
| ID: mdl-16671431
In this study, we investigated 40 patients (18 male, 22 female; mean age = 64.5 +/- 11.0; GCS = 9 to 14) with acute supratentorial spontaneous intracerebral hemorrhage (SICH) at admission by using a 1-tesla magnetic resonance imaging (MRI) unit equipped for single-shot echo-planar spin-echo isotropic diffusion-weighted imaging (DWI) sequences. All DWI studies were obtained within 48 hours after symptom onset. Regional apparent diffusion coefficient (rADC) values were measured in 3 different regions of interest (ROIs) drawn freehand on the T2-weighted images at b 0 s/mm2 on every section in which hematoma was visible: 1) the perihematomal hyperintense area; 2) 1 cm of normal appearing brain tissue surrounding the perilesional hyperintense rim; 3) an area mirroring the region including the clot and perihematomal hyperintense area placed in the contralateral hemisphere. rADC mean values were higher in perihematomal hyperintense and in contralateral than in normal appearing areas (p < 0.001), with increased rADC mean levels in all regions examined. Our findings show that rADC values indicative of vasogenic edema were present in the perihematomal area and in normal appearing brain tissue located both ipsilateral and contralateral to the hematoma, with lower levels in non-injured areas located in the T2 hyperintense rim around the clot.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Interpretación de Imagen Asistida por Computador
/
Hemorragia Cerebral
/
Imagen de Difusión por Resonancia Magnética
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Neurochir Suppl
Año:
2006
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Austria