[Inhalation of organic solvents during the last third of pregnancy in Sprague-Dawley rats. Somatometric and cerebellar consequences in newborn animals]. / Inhalación de solventes orgánicos durante el último tercio del embarazo de ratas Sprague-Dawley. Consecuencias somatométricas y cerebelosas en neonatos.
Arch Invest Med (Mex)
; 21(4): 311-7, 1990.
Article
en Es
| MEDLINE
| ID: mdl-1669219
ABSTRACT
Cerebellar morphogenesis as well as somatometric parameters of progenies from mothers exposed to ethyl-ether, chloroform, turpentine or thinner were registered a 24, 48 and 7 hours of age. 1. Mortality rate of 20 and 59% was observed in progenies of thinner or turpentine exposed mothers, correspondingly. 2. Delay of intrauterine growth manifested by body weight, size and cephalic diameter was evident in chloroform exposed groups (P < 0.01). 3. Cerebellar maturation delay was found in thinner or turpentine prenatally exposed litters. 4. The number of Purkinje cells was significantly reduced in ethyl-ether and chloroform exposed groups (P < 0.01). These cells were found less affected by thinner or turpentine exposure (P < 0.01).
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Solventes
/
Anomalías Inducidas por Medicamentos
/
Preñez
/
Enfermedades Cerebelosas
/
Retardo del Crecimiento Fetal
Límite:
Animals
/
Pregnancy
Idioma:
Es
Revista:
Arch Invest Med (Mex)
Año:
1990
Tipo del documento:
Article