Comparison between endoscopic brush cytology performed before and after biliary stricture dilation for cancer detection.
Arq Gastroenterol
; 43(1): 20-3, 2006.
Article
en En
| MEDLINE
| ID: mdl-16699613
ABSTRACT
BACKGROUND:
Confirmation of malignancy within biliary strictures is endoscopically challenging. Dilation of strictures has been reported to enhance cytological diagnosis.AIM:
To compare brush cytology results before and after biliary stricture dilation. PATIENTS ANDMETHODS:
Patients with extra-hepatic biliary stricture at endoscopic retrograde cholangiopancreatography were included in the study. Brushing was performed before and immediately after dilation using a 10 Fr dilating catheter. Cytology samples were classified as negative for malignancy, presence of atypical cells, insufficient material, suspicious for malignancy or positive for malignancy. Final diagnosis was established by surgery, biopsy or follow-up.RESULTS:
Biliary brush cytology was performed in 50 patients, with an overall sensitivity of 40% and 27.5%, before and after dilation, respectively. The combination of results increased cancer detection rate to 45%. There were 5/50 (10%) minor complications and one death related to the procedure.CONCLUSIONS:
Brush cytology performed before biliary stricture dilation has a similar cancer detection rate to that following dilation, although the combination of results enhances sensitivity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Pancreáticas
/
Colestasis Extrahepática
/
Neoplasias del Sistema Biliar
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Aged80
/
Humans
/
Middle aged
Idioma:
En
Revista:
Arq Gastroenterol
Año:
2006
Tipo del documento:
Article
País de afiliación:
Brasil