Glutathione peroxidase deficiency and childhood seizures.
Lancet
; 337(8755): 1443-4, 1991 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-1675321
ABSTRACT
4 children with intractable seizures, repeated infections, and intolerance to anticonvulsants had evidence of glutathione peroxidase deficiency. 2 had low intracellular enzyme activity but normal blood selenium and high plasma glutathione peroxidase concentrations. The other 2 had low intracellular glutathione peroxidase activity with low circulating glutathione peroxidase and selenium concentrations. The clinical state of the children improved after discontinuation of anticonvulsant medication and selenium substitution.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Convulsiones
/
Glutatión Peroxidasa
/
Glutatión Reductasa
Límite:
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Lancet
Año:
1991
Tipo del documento:
Article