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Mechanisms of hepatoprotective effect of preparation containing superlow doses of antibodies to granulocytic colony-stimulating factor.
Epstein, O I; Zyuz'kov, G N; Sotnikova, N V; Stavrova, L A; Fomina, T I; Vetoshkina, T V; Sergeeva, S A; Dubskaya, T Yu; Dygai, A M; Gol'dberg, E D.
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  • Epstein OI; Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences.
Bull Exp Biol Med ; 140(5): 598-602, 2005 Nov.
Article en En | MEDLINE | ID: mdl-16758635
The hepatoprotective effects of superlow dose preparation of antibodies to granulocytic CSF were studied on a model of CCl4-induced hepatitis. The preparation exhibited high antiinflammatory and antisclerotic activities determined by stimulation, mobilization, and determined homing of mesenchymal stem cells into damaged liver with subsequent differentiation of these cells into mature hepatocytes.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor Estimulante de Colonias de Granulocitos / Hígado / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Bull Exp Biol Med Año: 2005 Tipo del documento: Article Pais de publicación: Estados Unidos
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor Estimulante de Colonias de Granulocitos / Hígado / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Bull Exp Biol Med Año: 2005 Tipo del documento: Article Pais de publicación: Estados Unidos