Transient left ventricular apical ballooning after cocaine use: is catecholamine cardiotoxicity the pathologic link?
Mayo Clin Proc
; 81(6): 829-32, 2006 Jun.
Article
en En
| MEDLINE
| ID: mdl-16770985
ABSTRACT
We describe a patient who developed acute chest pain after using cocaine and had ST-segment elevation in the anterior leads on electrocardiography with mild elevation of cardiac enzymes. Cardiac catheterization showed normal coronary arteries with no coronary vasospasm. Left ventricular angiography revealed typical ballooning of the left ventricular apex during systole with an estimated left ventricular ejection fraction of 25%. The symptoms improved during the next few hours, and follow-up echocardiography 4 days later showed complete resolution of the left ventricular dysfunction. Transient left ventricular apical ballooning (LVAB) was diagnosed. To our knowledge, LVAB (also known as Takotsubo cardiomyopathy or "broken heart syndrome") has not been reported previously in association with cocaine use. We discuss the possible pathophysiologic link between LVAB and cocaine-induced cardiotoxicity.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Catecolaminas
/
Cocaína Crack
/
Disfunción Ventricular Izquierda
/
Cardiomiopatías
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Mayo Clin Proc
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos