Achieving directed immunostimulating complexes incorporation.
Expert Rev Vaccines
; 5(3): 395-403, 2006 Jun.
Article
en En
| MEDLINE
| ID: mdl-16827623
ABSTRACT
In recent years, several studies have been reported with the common aim of generating general expression systems for straightforward production and subsequent coupling of expressed antigens to an adjuvant system. Here, we describe a series of such efforts with a common theme of using gene fusion technology for association of recombinant antigens to immunostimulating complexes (iscoms). In the early stages of vaccine development, uniform antigen preparations are crucial to allow the comparison of immune responses to different antigens, or even subdomains thereof, and we believe that the described systems constitute an important development in this context.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ISCOMs
/
Vacunas de Subunidad
/
Antígenos
Límite:
Animals
Idioma:
En
Revista:
Expert Rev Vaccines
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Suecia