CHMP2B mutations are not a cause of dementia in Dutch patients with familial and sporadic frontotemporal dementia.
Am J Med Genet B Neuropsychiatr Genet
; 141B(8): 944-6, 2006 Dec 05.
Article
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| MEDLINE
| ID: mdl-16941655
ABSTRACT
Mutations in the CHMP2B gene have been recently identified in a large Danish pedigree with autosomal dominant frontotemporal dementia (FTD) linked to chromosome 3 (FTD3). We report the frequency of CHMP2B mutations in 162 FTD patients recruited from a large population-based study of FTD carried out in The Netherlands. Our results suggest that mutations in CHMP2B are a rare cause of FTD as compared to MAPT mutations.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Demencia
/
Mutación
/
Proteínas del Tejido Nervioso
Límite:
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Am J Med Genet B Neuropsychiatr Genet
Asunto de la revista:
GENETICA MEDICA
/
NEUROLOGIA
/
PSIQUIATRIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Países Bajos