Hearing loss in Turner syndrome.
J Pediatr
; 149(5): 697-701, 2006 Nov.
Article
en En
| MEDLINE
| ID: mdl-17095347
ABSTRACT
OBJECTIVE:
To address the characteristics of hearing loss in patients with Turner syndrome (TS), we evaluated hearing levels of patients with TS and analyzed causative factors. STUDYDESIGN:
Thirty-three patients with TS (8 to 40 years of age) were studied through the use of audiological measurements, and causative factors were explored.RESULTS:
Twenty cases (35 of 66 ears tested) showed high-frequency (8 kHz) sensory neural hearing loss (HFQ-SNHL). Fifteen cases (26 ears) and 15 cases (24 ears) of the impaired 20 cases were unresponsive to distortion-product otoacoustic emissions and transient-evoked otoacoustic emissions, respectively. HFQ-SNHL showed little relation to the history of middle ear infection and puberty, although middle ear infections were seen in 11 of the 20 cases. The hearing thresholds at high frequencies were correlated with age and body height (P < .001). The age-dependent increase in hearing thresholds in the high frequencies was more apparent in patients with TS with monosomic 45, X than in those with the mosaic type (P < .05).CONCLUSIONS:
More than 60% of patients with TS had HFQ-SNHL. Because the increase in hearing threshold at high frequencies was shown to depend on karyotype and aging, regular otological examination is important for the determination of proper treatment.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Turner
/
Pérdida Auditiva
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
Idioma:
En
Revista:
J Pediatr
Año:
2006
Tipo del documento:
Article
País de afiliación:
Japón