[Advances of research on abnormality of cell immunity in idiopathic thrombocytopenic purpura: review].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
; 14(5): 1045-8, 2006 Oct.
Article
en Zh
| MEDLINE
| ID: mdl-17096917
ABSTRACT
It was long believed that platelets are prematurely destroyed in the reticuloendothelial system by platelet autoantibodies in idiopathic thrombocytopenic purpura. However, humoral mechanisms cannot account for all observations made in this disorder, and it is increasingly evident that cellular mechanisms contribute to platelet destruction. In this review the tolerance of T cell, abnormality of T cell apoptosis, abnormal activation of T cells, T cell subtype and its function changes, and T cell-mediated cytotoxicity were summarized.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Linfocitos T
/
Linfocitos T Citotóxicos
/
Púrpura Trombocitopénica Idiopática
Límite:
Humans
Idioma:
Zh
Revista:
Zhongguo Shi Yan Xue Ye Xue Za Zhi
Asunto de la revista:
HEMATOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
China