Physical activity and risk of colon cancer in a cohort of Danish middle-aged men and women.
Eur J Epidemiol
; 21(12): 877-84, 2006.
Article
en En
| MEDLINE
| ID: mdl-17160429
ABSTRACT
OBJECTIVE:
To investigate the effects of occupational activity and leisure time activity on incident colon cancer risk in a Danish middle-aged population.METHODS:
In the cohort, Diet, Cancer and Health, which included 28,356 women and 26,122 men aged 50-64 years at baseline, 140 women and 157 men were diagnosed with colon cancer from 1993 to 2003. The associations between occupational and leisure time activity in terms of a MET-score and the single activities, sports, cycling, walking, gardening, housework and do-it-yourself work, and incident colon cancer were investigated. Leisure time activity was investigated in two ways using the Cox proportional hazards model by comparison of active versus non-active and by investigating a possible dose-response relationship while allowing a separate association for non-active individuals.RESULTS:
No associations were found between risk of colon cancer and occupational activity, MET-hours per week of total leisure time activity, residuals from a regression of each activity on the total MET-hours or the time spent on any of the six types of leisure time activities. However, a borderline significant association was found with the number of activities in which the participants were active. For each additional activity IRR = 0.87 (0.76-1.00) for women and IRR = 0.88 (0.78-1.00) for men.CONCLUSION:
Our data do not support the evidence of an inverse association between colon cancer risk and occupational activity or leisure time activity, but avoiding a sedentary lifestyle by participating in different activities may reduce colon cancer risk.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Recreación
/
Trabajo
/
Neoplasias del Colon
/
Estilo de Vida
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
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Male
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Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur J Epidemiol
Asunto de la revista:
EPIDEMIOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Dinamarca