A ventricular pressure-clamping system for the study of mechano-electrical feedback.
Sheng Li Xue Bao
; 58(6): 606-10, 2006 Dec 25.
Article
en En
| MEDLINE
| ID: mdl-17173197
ABSTRACT
It is necessary to control the mechanical stimuli precisely in the studies of cardiac mechano-electrical feedback (MEF). In the present study a ventricular pressure-clamping system has been developed, which can be applied to isolated-perfused rabbit hearts. Controlled by a computer, this system not only can make the left ventricle follow a command defining the same pressure wave as that during a beating cycle under physiological condition, but also deliver mechanical stimuli with a proper waveform to the ventricle at a particular time phase. This system integrates multiple functions, including perfusing, pacing, recording of electrocardiogram and monophasic action potentials, and clamping and measuring of ventricular pressures in isolated-perfused hearts. Thus, it is a distinct system for investigating the phenomena and mechanisms of cardiac MEF at organ level.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Presión Ventricular
/
Retroalimentación
/
Corazón
Límite:
Animals
Idioma:
En
Revista:
Sheng Li Xue Bao
Año:
2006
Tipo del documento:
Article
País de afiliación:
China