Cytotoxic farnesyl glycosides from Pittosporum pancheri.
Phytochemistry
; 68(5): 604-8, 2007 Mar.
Article
en En
| MEDLINE
| ID: mdl-17174992
ABSTRACT
Bioassay guided purification of the ethanolic extract of the bark of New Caledonian Pittosporum pancheri Brongn. and Gris (Pittosporaceae) led to the isolation and characterization of two new farnesyl monoglycosides, pancherins A and B. The structure of these compounds were determined on the basis of spectroscopic studies. The new compounds displayed a significant activity in the in vitro cytotoxic assay against KB cancer cell line, and pancherin A inhibits weakly farnesyl protein transferase.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Rosales
/
Glicósidos
Límite:
Humans
Idioma:
En
Revista:
Phytochemistry
Año:
2007
Tipo del documento:
Article
País de afiliación:
Francia