Drug-induced pericarditis mimicking Brugada syndrome.
Europace
; 9(1): 66-8, 2007 Jan.
Article
en En
| MEDLINE
| ID: mdl-17224428
ABSTRACT
Brugada syndrome (BS) is associated with sudden cardiac death in patients with a structurally normal heart. The ECG pattern of BS has also been described in patients with myocardial abnormalities. Cardiac hypersensitivity and myopericarditis have been reported during long-term treatment with mesalazine. We report the case of a man, treated with mesalazine for Crohn's disease who developed drug-induced pericarditis. The ECG showed a coved ST-segment elevation in the right precordial leads V1-V3, a pattern mimicking BS. The ECG normalized in a few days after mesalazine withdrawal and the follow-up was uneventful. The ECG remained normal. Two ajmaline tests were both negative and ruled out the diagnosis of BS. This observation illustrates that a coved ST-segment elevation in the right precordial leads should not be, systematically, regarded as a marker of a specific syndrome, but may also reflect a common electrical manifestation of abnormalities in the right ventricle or pericardium.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pericarditis
/
Antiinflamatorios no Esteroideos
/
Mesalamina
/
Síndrome de Brugada
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Europace
Asunto de la revista:
CARDIOLOGIA
/
FISIOLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Francia