Oxidative stress as determined by glutathione (GSH) concentrations in venous cord blood in elective cesarean delivery versus uncomplicated vaginal delivery.
Arch Gynecol Obstet
; 276(1): 43-6, 2007 Jul.
Article
en En
| MEDLINE
| ID: mdl-17333227
ABSTRACT
OBJECTIVE:
To determine whether neonates are subject to oxidative stress by the labor process and the mode of delivery by measuring glutathione (GSH) concentrations in umbilical cord venous blood. STUDYDESIGN:
Forty-eight women with singleton term pregnancies were prospectively recruited and classified as follows 26 women had a spontaneous uncomplicated vaginal delivery (VD), and 22 women had an elective cesarean delivery (CD). GSH concentration in umbilical venous blood samples was determined by a spectroscopic method.RESULTS:
Umbilical cord venous blood GSH levels were significantly lower in the elective CD group than in the VD group (2.2 and 2.7 mM, respectively, P = 0.0003). There was a significantly negative correlation between cord blood pO(2) and GSH levels; however, the negative correlation was significantly higher in the elective CD group (P < 0.05).CONCLUSION:
Neonates delivered by CD were exposed to a higher oxidative stress as determined by GSH levels compared to those who had an uncomplicated VD.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cesárea
/
Estrés Oxidativo
/
Sangre Fetal
/
Glutatión
Tipo de estudio:
Observational_studies
Límite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Arch Gynecol Obstet
Asunto de la revista:
GINECOLOGIA
/
OBSTETRICIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Israel