DNA replication and models for the origin of piRNAs.
Bioessays
; 29(4): 382-5, 2007 Apr.
Article
en En
| MEDLINE
| ID: mdl-17373697
The piRNA class of small RNAs are distinct from other small RNAs by their approximately 26-31 nucleotide size, single-strandedness and strand-specificity as well as by the clustered arrangement of their origins. Here, we highlight how these features are reminiscent of the mechanisms of DNA replication, and then present three models suggesting that the origin of piRNAs may be mechanistically similar to key processes in DNA replication.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ARN
/
Replicación del ADN
/
Modelos Genéticos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Bioessays
Asunto de la revista:
BIOLOGIA
/
BIOLOGIA MOLECULAR
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos