Aerosol and subcutaneous measles vaccine: measles antibody responses 6 years after re-vaccination.
Vaccine
; 25(21): 4170-4, 2007 May 22.
Article
en En
| MEDLINE
| ID: mdl-17408818
ABSTRACT
There are no large-scale data on the long-term persistence of measles antibody after vaccination by the aerosol route. We therefore followed-up South African schoolchildren 6 years after their re-vaccination with Edmonston-Zagreb (EZ) and Schwarz (SW) measles vaccine given by aerosol and subcutaneous routes. Measles antibody levels and the proportion of children who were seropositive at year 6 remained significantly higher in the Edmonston-Zagreb aerosol group compared to the groups that received Schwarz or Edmonston-Zagreb vaccine subcutaneously. Measles re-vaccination by aerosol evokes a stronger and much longer lasting antibody response than injected vaccine and should thus provide more durable protection against measles.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vacuna Antisarampión
/
Sarampión
/
Virus del Sarampión
/
Anticuerpos Antivirales
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Región como asunto:
Africa
Idioma:
En
Revista:
Vaccine
Año:
2007
Tipo del documento:
Article
País de afiliación:
Sudáfrica