Estimation of delay in detecting hepatitis C virus antibodies in pools compared to individual testing on seroconversion panels.
Clin Microbiol Infect
; 13(7): 737-9, 2007 Jul.
Article
en En
| MEDLINE
| ID: mdl-17441976
ABSTRACT
Testing for anti-hepatitis C virus (HCV) antibodies in pools may reduce blood screening costs, making this approach affordable for developing countries, provided that the dilution of infected blood does not significantly increase the number of undetectable viral particles, especially in seroconverters. This study assessed the delay in detection of HCV antibodies in five HCV seroconversion panels, tested in pools of 6-48 samples, and estimated the risk of transfusion-transmitted HCV caused by pooling. The delay in detection of positive samples was 5-12 days for pools of all sizes, adding 7% to the risk of HCV transmission that occurs when blood donors' samples are tested individually.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Donantes de Sangre
/
Recolección de Muestras de Sangre
/
Hepatitis C
/
Hepacivirus
/
Anticuerpos contra la Hepatitis C
Tipo de estudio:
Evaluation_studies
Límite:
Humans
Idioma:
En
Revista:
Clin Microbiol Infect
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Israel