[Electrophysiological aspects of intermediate syndrome in organophosphate poisonings]. / Aspects électrophysiologiques du syndrome intermédiaire au cours des intoxications aux organophosphorés.
Rev Neurol (Paris)
; 163(4): 480-2, 2007 Apr.
Article
en Fr
| MEDLINE
| ID: mdl-17452951
ABSTRACT
Acute organophosphate poisoning, whether accidental or suicidal, is frequent in developing countries and produces significant morbidity and mortality. Organophosphates inhibit cholinesterase activity at the neuromuscular junction and cause extensive muscle paralysis, particularly for respiratory function. Poisonings evolve in three stages cholinesterase crisis, intermediate syndrome and delayed neuropathy. Electrophysiological aspects have been poorly studied. We report the case of a 25-year-old woman admitted to intensive care unit with muscarinic signs and respiratory failure after attempted suicidal organophosphate poisoning. Cholinesterase activity was low and the electrophysiological study disclosed the characteristic aspect of intermediate syndrome. The patient died due to septic complications. This syndrome is exceptional with a poorly understood pathophysiology. The electrophysiological study is essential for diagnosis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inhibidores de la Colinesterasa
/
Intoxicación por Organofosfatos
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
Fr
Revista:
Rev Neurol (Paris)
Año:
2007
Tipo del documento:
Article
País de afiliación:
Marruecos