Infection scintigraphy: added value of single-photon emission computed tomography/computed tomography fusion compared with traditional analysis.
J Comput Assist Tomogr
; 31(3): 375-80, 2007.
Article
en En
| MEDLINE
| ID: mdl-17538282
ABSTRACT
PURPOSE:
Positron emission tomography (PET)/computed tomography (CT) imaging is a powerful dual-modality integrating physiology and anatomy. Analogously, fusing separate single-photon emission computed tomography (SPECT) and CT images can overcome interpretive challenges in characterizing and localizing abnormalities. This study explores the value of SPECT/CT image fusion compared with traditional "side-by-side" SPECT-CT image review for infectious /inflammatory processes. METHODS AND MATERIALS We identified 17 abnormal infection/inflammation SPECT scans in 16 patients (11 indium 111 WBC and 6 gallium citrate Ga 67) with a contemporary CT scan. The SPECT and CT images were uploaded onto "side-by-side" workstations, one with fusion software. Two nuclear radiologists reviewed "side-by-side" SPECT and CT images and fused SPECT/CT images. They scored 2 parameters (anatomical localization and diagnostic confidence) using a 4-point scale (1 "not helpful" to 4 "very helpful"). Score differences more than 1 indicated "added value" and less than 0, "no added value".RESULTS:
Compared with "side-by-side" SPECT-CT, fused SPECT/CT images yielded "added value" for anatomical localization in 65%, diagnostic confidence in 71%, and altered interpretations in 47% of cases. Greater confidence was achieved in 75% of cases with altered interpretations and 55% of unaltered cases.CONCLUSIONS:
The SPECT/CT image fusion outperformed "side-by-side" SPECT/CT review for anatomical localization and diagnostic confidence of infectious/inflammatory abnormalities. Therefore, SPECT/CT fusion potentially influences clinical decisions and treatment options.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tomografía Computarizada por Rayos X
/
Tomografía Computarizada de Emisión de Fotón Único
/
Infecciones
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Comput Assist Tomogr
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos