"Clusters" of CJD in Slovakia: the first statistically significant temporo-spatial accumulations of rural cases.
Eur J Epidemiol
; 7(5): 450-6, 1991 Sep.
Article
en En
| MEDLINE
| ID: mdl-1761101
ABSTRACT
A space-time analysis of clustering among 78 definite CJD cases who died in Slovakia (75) and an adjacent part of Hungary (3) during 1972-1991 is presented. Two geographical rural accumulations of sporadic and familial CJD patients in the north and south of Central Slovakia were found. There was evidence of two significant clusters when spatial and temporal neighborhoods were defined by distances of 2,4,5 and 7 km within 1.5 and 2 years. Involvement of genetic mechanisms in the clusters was demonstrated, and the possible role of environmental (zoonotic) risk factors are considered.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Creutzfeldt-Jakob
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Epidemiol
Asunto de la revista:
EPIDEMIOLOGIA
Año:
1991
Tipo del documento:
Article