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HBV serological markers of vaccinated children in remote areas of Taiwan: emphasis on factors contributing to vaccine failure.
Huang, Mei-Liang; Liao, Wen-Ling; Ho, Mei-Shang.
Afiliación
  • Huang ML; College of Public Health, National Taiwan University, Taipei, Taiwan.
Vaccine ; 25(34): 6326-33, 2007 Aug 21.
Article en En | MEDLINE | ID: mdl-17629600
A serosurvey targeting Hepatitis B virus (HBV)-vaccinated children born between 1986 and 1998 was conducted in 2001 in remote Taiwanese villages where a 1993 serosurvey indicated high vaccine failure. The HBV S antigen (HBsAg) seropositive rate among vaccinees of 3-6-year-old children in 2001 was significantly lower than that of 1993 and was higher among children who had a delayed vaccination schedule and received the plasma-derived vaccine. Vaccine escape variants were more prevalent among recipients of recombinant HBV vaccine residing in Hualien. Our study highlights the importance of continued monitoring of vaccinees for incidence of HBV infection in order to refine future vaccination policy.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunación / Vacunas contra Hepatitis B / Anticuerpos contra la Hepatitis B / Antígenos de Superficie de la Hepatitis B Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Vaccine Año: 2007 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Países Bajos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunación / Vacunas contra Hepatitis B / Anticuerpos contra la Hepatitis B / Antígenos de Superficie de la Hepatitis B Tipo de estudio: Prevalence_studies / Risk_factors_studies Límite: Child / Child, preschool / Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Vaccine Año: 2007 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Países Bajos