Bioaccumulation of explosive compounds in the marine mussel, Mytilus galloprovincialis.
Ecotoxicol Environ Saf
; 68(2): 237-45, 2007 Oct.
Article
en En
| MEDLINE
| ID: mdl-17629944
ABSTRACT
The bioaccumulative potential of the explosive compounds, 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) were assessed in water only exposures with the Mediterranean mussel (Mytilus galloprovincialis). Toxicokinetics experiments provided uptake rates, elimination rates, biological half-lives, and bioconcentration factors (BCFs). Kinetic BCFs were 1.61, 0.87, and 0.44, for TNT, RDX, and HMX, respectively, and confirmed the expected low bioaccumulative potential of these weakly hydrophobic compounds based on logK(ow). Because apparent steady-state conditions were observed within the 4h uptake period, steady-state BCFs were also calculated, and were within 20% of kinetic BCFs. TNT was rapidly biotransformed to aminodinitrotoluenes within minutes, while no transformation products were measured for RDX or HMX. Uptake clearance rates varied among the compounds, while elimination rates and associated half-lives were extremely fast (0.15-0.49h). It is unlikely, based on these data, that exposure conditions for these explosive compounds in the marine environment pose unacceptable risks to mussels, and it appears that potential for trophic transfer is quite low.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Azocinas
/
Triazinas
/
Contaminantes Químicos del Agua
/
Trinitrotolueno
/
Mytilus
/
Sustancias Explosivas
/
Compuestos Heterocíclicos con 1 Anillo
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos