Clinical and imaging characterization of a patient with idiopathic progressive ataxia and palatal tremor.
Eur J Neurol
; 14(8): 944-6, 2007 Aug.
Article
en En
| MEDLINE
| ID: mdl-17662021
ABSTRACT
We describe clinical and imaging features of a patient with sporadic progressive ataxia and palatal tremor (PAPT) of unknown etiology. There was hypertrophy of bilateral inferior olivary nuclei with hyperintense T2-weighted signal and mild cerebellar atrophy at brain magnetic resonance imaging. 18F-fluoro-2-desoxy-d-glucose positron emission tomography scanning (FDG-PET) showed hypometabolism in the red nucleus, external globus pallidus and precuneus while FP-CIT-SPECT imaging revealed mild and progressive loss of striatal dopaminergic terminals. Our findings suggest that in idiopathic PAPT involvement of the dentato-rubro-olivary pathway occurs along with some dopaminergic dysfunction.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de los Ganglios Basales
/
Disinergia Cerebelosa Mioclónica
/
Dopamina
/
Ataxia Cerebelosa
/
Mioclonía
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Eur J Neurol
Asunto de la revista:
NEUROLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Italia