BiasViz: visualization of amino acid biased regions in protein alignments.
Bioinformatics
; 23(22): 3093-4, 2007 Nov 15.
Article
en En
| MEDLINE
| ID: mdl-17921493
ABSTRACT
About a third of all protein sequences have at least one composition biased region (CBR). Such regions might act as linkers between protein domains but often confer specific binding to various molecules; therefore, their characterization in terms of their boundaries and over-represented residues is important. Analysis of CBRs in a particular sequence can be time consuming if several types of biases have to be explored and their position visualized. Assessment of the significance of the detected CBRs can be approached by comparison to homologous protein sequences. To assist this procedure, we have developed BiasViz, a tool that allows to graphically studying local amino acid composition in protein sequences of a multiple sequence alignment.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Algoritmos
/
Gráficos por Computador
/
Interfaz Usuario-Computador
/
Proteínas
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Alineación de Secuencia
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Análisis de Secuencia de Proteína
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Aminoácidos
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Canadá