Rintact: enabling computational analysis of molecular interaction data from the IntAct repository.
Bioinformatics
; 24(8): 1100-1, 2008 Apr 15.
Article
en En
| MEDLINE
| ID: mdl-17989096
ABSTRACT
MOTIVATION The IntAct repository is one of the largest and most widely used databases for the curation and storage of molecular interaction data. These datasets need to be analyzed by computational methods. Software packages in the statistical environment R provide powerful tools for conducting such analyses. RESULTS:
We introduce Rintact, a Bioconductor package that allows users to transform PSI-MI XML2.5 interaction data files from IntAct into R graph objects. On these, they can use methods from R and Bioconductor for a variety of tasks determining cohesive subgraphs, computing summary statistics, fitting mathematical models to the data or rendering graphical layouts. Rintact provides a programmatic interface to the IntAct repository and allows the use of the analytic methods provided by R and Bioconductor.AVAILABILITY:
Rintact is freely available at http//bioconductor.org
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lenguajes de Programación
/
Interfaz Usuario-Computador
/
Programas Informáticos
/
Almacenamiento y Recuperación de la Información
/
Mapeo de Interacción de Proteínas
/
Bases de Datos de Proteínas
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Reino Unido