The ovarian endothelin network: an evolving story.
Trends Endocrinol Metab
; 18(10): 379-85, 2007 Dec.
Article
en En
| MEDLINE
| ID: mdl-17997104
ABSTRACT
The endothelin (ET) system consists of three ET isopeptides, several converting enzyme isoforms and two G-protein-coupled receptors, ETA and ETB, which are linked to multiple signaling pathways. Less than 20 years after the initial detection of ET-1 in granulosa cells, the ovarian ET network continues to expand with the discovery of new members and functions. ETs influence a broad range of essential reproductive processes, such as ovulation, steroidogenesis and luteolysis. Therefore, a more comprehensive understanding of the ovarian ET network might provide new strategies for controlling reproduction. This review presents up-to-date findings on the ET network in the ovary.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ovario
/
Endotelinas
Límite:
Female
/
Humans
Idioma:
En
Revista:
Trends Endocrinol Metab
Asunto de la revista:
ENDOCRINOLOGIA
/
METABOLISMO
Año:
2007
Tipo del documento:
Article
País de afiliación:
Israel