Efficacy of azithromycin in preventing pulmonary abscesses in foals.
Vet J
; 179(2): 301-3, 2009 Feb.
Article
en En
| MEDLINE
| ID: mdl-18023599
ABSTRACT
The prophylactic application of azithromycin to prevent pulmonary abscesses in foals was evaluated on a stud with endemic Rhodococcus equi pneumonia. Forty-five foals served as untreated controls in two groups. Twenty-five foals were given azithromycin (10mg/kg) orally once daily for 4 weeks. The foals were examined once a week from birth to the age of 5 months. If clinical signs or leucocytosis were noted and pulmonary sonographic findings (diameter >10 mm) were observed, the diagnosis of abscessing pneumonia was made. The prevalence of pulmonary abscesses was similar in the control groups (31/45 foals), and in the azithromycin group (15/25 foals), but the foals in the azithromycin group were affected significantly later (median day 83, range 67-123 days) (control groups day 54, range 52-82; and 46, range 28-86 days). It was concluded that the application of azithromycin for 28 days post-natally does not reduce the prevalence of pulmonary abscesses in foals on a stud with endemic pneumonia.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Azitromicina
/
Neumonía Bacteriana
/
Enfermedades de los Caballos
/
Absceso Pulmonar
/
Antibacterianos
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
Vet J
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Alemania