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Cell-to-cell fusion as a link between viruses and cancer.
Duelli, Dominik; Lazebnik, Yuri.
Afiliación
  • Duelli D; Department of Pathology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA. lazebnik@cshl.edu
Nat Rev Cancer ; 7(12): 968-76, 2007 12.
Article en En | MEDLINE | ID: mdl-18034186
The ability to fuse cells is shared by many viruses, including common human pathogens and several endogenous viruses. Here we will discuss how cell fusion can link viruses to cancer, what types of cancers it can affect, how the existence of this link can be tested and how the hypotheses that we propose might affect the search for human oncogenic viruses. In particular, we will focus on the ability of cell fusion that is caused by viruses to induce chromosomal instability, a common affliction of cancer cells that has been thought to underlie the malignant properties of cancerous tumours.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus Oncogénicos / Internalización del Virus / Fusión de Membrana / Neoplasias Límite: Humans Idioma: En Revista: Nat Rev Cancer Asunto de la revista: NEOPLASIAS Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus Oncogénicos / Internalización del Virus / Fusión de Membrana / Neoplasias Límite: Humans Idioma: En Revista: Nat Rev Cancer Asunto de la revista: NEOPLASIAS Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido