A double-blind comparative study of doxazosin and prazosin in the treatment of essential hypertension.
Am Heart J
; 121(1 Pt 2): 317-22, 1991 Jan.
Article
en En
| MEDLINE
| ID: mdl-1824654
ABSTRACT
Two hundred sixty-six patients took part in a multicenter comparative study of doxazosin and prazosin. Both drugs produced a significant reduction (p less than 0.001) in blood pressure and no increase in heart rate. Blood pressure was considered "markedly decreased" or "decreased" in 70.8% of patients treated with doxazosin and 70.0% of patients treated with prazosin. No statistically significant between-group differences in antihypertensive efficacy were observed. Both doxazosin and prazosin were well tolerated; seven patients (5.6%) in each group had the therapy withdrawn.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Prazosina
/
Hipertensión
/
Antihipertensivos
Tipo de estudio:
Clinical_trials
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am Heart J
Año:
1991
Tipo del documento:
Article
País de afiliación:
Japón