Impaction grafting with a bone-graft substitute in a sheep model of revision hip replacement.
J Bone Joint Surg Br
; 90(2): 246-53, 2008 Feb.
Article
en En
| MEDLINE
| ID: mdl-18256099
ABSTRACT
An experimental sheep model was used for impaction allografting of 12 hemiarthroplasty femoral components placed into two equal-sized groups. In group 1, a 5050 mixture of ApaPore hydroxyapatite bone-graft substitute and allograft was used. In group 2, ApaPore and allograft were mixed in a 9010 ratio. Both groups were killed at six months. Ground reaction force results demonstrated no significant differences (p > 0.05) between the two groups at 8, 16 and 24 weeks post-operatively, and all animals remained active. The mean bone turnover rates were significantly greater in group 1, at 0.00206 mm/day, compared to group 2 at 0.0013 mm/day (p < 0.05). The results for the area of new bone formation demonstrated no significant differences (p > 0.05) between the two groups. No significant differences were found between the two groups in thickness of the cement mantle (p > 0.05) and percentage ApaPore-bone contact (p > 0.05). The results of this animal study demonstrated that a mixture of ApaPore allograft in a 9010 ratio was comparable to using a 5050 mixture.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Osteogénesis
/
Biomarcadores
/
Trasplante Óseo
/
Sustitutos de Huesos
/
Artroplastia de Reemplazo de Cadera
/
Fémur
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
J Bone Joint Surg Br
Año:
2008
Tipo del documento:
Article
País de afiliación:
Reino Unido